The Topi-CLICK® Way

Topi-CLICK® Questions and Answers

What is Topi-CLICK®?

Topi-CLICK® is a line of metered-dose applicators that pharmacies fill with compounded topical creams, gels and ointments for human and veterinary patients. Each turn of the base gives an audible, visible and tactile CLICK and dispenses a set volume, and the built-in applicator lets patients apply the dose without getting medication on their hands. Topi-CLICK launched in 2007 and is made by Cordica Medical, formerly TEAM Technologies.

How accurate is Topi-CLICK compared with syringes and other dispensers?

In an independent study by Analytical Research Laboratories (ARL) in Oklahoma City, Topi-CLICK® was the most accurate of the topical metered-dosing applicators tested; the report concluded that it “performed with remarkable precision and accuracy compared to the other dispensers.” In weight checks with Medisca and PCCA HRT cream bases, two-CLICK doses had coefficients of variation of 3.16% and 3.28%. The plunger works like a syringe’s but moves in fixed steps, so patients count CLICKs instead of reading syringe markings. A separate ARL study found the Topi-CLICK Perl® more accurate than traditional vaginal dosing methods. Request a copy of the accuracy study.

How much does one CLICK dispense, and how many CLICKs are in a dose?

Each CLICK dispenses a fixed volume: 0.25 mL on the Topi-CLICK® 35 models (standard, Child Resistant, 3Port™ and Light SAFE™), the Perl® and the UD™ 45; 0.5 mL on the Topi-CLICK® 140; and 0.05 mL on the Topi-CLICK Micro®. The number of CLICKs per dose comes from the prescription, and two CLICKs is the most common dose. Priming before the first dose takes about two CLICKs on the 35 and 140 and three on the Micro.

Is there a child-resistant Topi-CLICK?

Yes. The Topi-CLICK® 35 Child Resistant meets U.S. Consumer Product Safety Commission criteria for child resistance under 16 CFR §1700.20 when fully assembled as specified. Its push-and-turn cap and pinch-grip DoseLock™ base must both be operated before any medication can be dispensed, and it doses the same 0.25 mL per CLICK as the standard Topi-CLICK 35. The Troche-CLICK™ is also available in child-resistant packaging.

What is the difference between the Topi-CLICK 35, 140, Micro and UD 45?

The Topi-CLICK® 35 holds 35 mL and dispenses 0.25 mL per CLICK, about 64 two-CLICK doses. The Topi-CLICK® 140 holds 140 mL at 0.5 mL per CLICK for larger-volume therapies such as pain management, wound care and scar care. The Topi-CLICK Micro® comes in 9 mL and 5 mL sizes at 0.05 mL per CLICK, with rounded, soft angled or pin point applicators, for micro-dosing in people and pets. The single-use Topi-CLICK® UD™ 45 holds 45 mL, about a three-month supply at two CLICKs a day, and also works as a mixing container for electronic mortar and pestle systems. Compare every model.

Can Topi-CLICK be used for pets?

Yes. Topi-CLICK applicators are made for human and veterinary patients, and the Topi-CLICK Micro®, at 0.05 mL per CLICK, was designed to micro-dose topical medications for people and pets.

Is Topi-CLICK registered with the FDA?

Yes. Topi-CLICK® is a registered FDA device, a Class I dispenser under product code KYX, FDA registration number 3007142798. It is made of FDA-grade materials that are BPA and phthalate free, with UV-blocking plastic. The FDA has not evaluated Topi-CLICK for use with specific prescription medications, so a licensed pharmacist should verify each formula and its weight-to-volume conversion before dispensing.

Does the thickness of a cream affect the dose?

Topi-CLICK® is designed to keep dosing consistent across thin, medium and thick formulations (Viscosity Assurance™). Every base and batch differs slightly, so pharmacists should calibrate each formulation, and some very viscous bases are not practical in a Topi-CLICK. The Topi-CLICK® 35 3Port™ is made for the thickest formulations.

Can a Topi-CLICK be reused or recycled?

Each Topi-CLICK is for one-time use. Next-generation dispensers have a recycling code molded into the base, and pharmacies should check with their State Board of Pharmacy before recycling prescription containers. Recycling information.

How do pharmacies order Topi-CLICK or request samples?

Pharmacies can order online on this site, through Topi-CLICK distributors, or by calling 877.870.8448. Free samples are available on request. Patients who would like a Topi-CLICK can ask their pharmacist or doctor.